The ETHYLENE RESPONSE FACTOR (ERF)-branch, which is co-regulated by ET, is activated upon infection with necrotrophic pathogens and is controlled by the AP2/ERF domain transcription factors ERF1 and ORA59, leading to transcription of PDF1.2, a marker gene of the JA/ET-regulated ERF-branch (Penninckx et al., 1998; Lorenzo et al., 2004; Pré et al., 2008). This evidence concerns the gene ERF and infection.