In another study performed by that team [34], Zucker obese rats (a model of the early stages of type 2 diabetes), CrProp lowered fasting plasma total, HDL, and LDL cholesterol, triglyceride concentrations, as well as insulin levels, and it lowered 2-h plasma insulin levels after 24 weeks of administration. The gene discussed is INS; the disease is type 2 diabetes mellitus.