SCH specimens in which time to fixation and fixation time were (1) 0 and 24 h, (2) 0 h and 10 days, (3) 6 and 24 h, (4) 24 and 24 h, or (5) 24 h and 10 days were assessed by FISH (HER2/CEP17 ratio). This evidence concerns the gene ERBB2 and spindle cell hemangioma.