A study performed in 2012 indicated that the C genotype of the rs6505162 SNP reduces the risk of breast cancer development, however, another study undertaken in 2009 suggested that the C genotype of rs6505162 offered an increased risk of developing both ovarian and breast cancer in Breast Cancer Associated 2 (BRCA2) mutation carriers26. The gene discussed is BRCA2; the disease is breast carcinoma.