A similar increase in the phosphorylation of SAPK/JNK at Thr183/Tyr185 was observed in the OCI-LY10 B-cell lymphoma line (Figure 5b) and in the SUP-T1 T-cell lymphoma line (data not shown) after exposure to [Gem+Clo+Ed] for 48 h. Here, MAPK8 is linked to B-cell non-Hodgkin lymphoma.