IGF1R and malignant colon neoplasm: Previous studies have identified that IGF1R is also a specific target of miR-145 in colon cancer cells [31], miR-122 in liver cancers [32], miR-7 in tongue squamous cell carcinoma cells [28], miR-375 in esophageal squamous cell carcinoma [33], and let-7c in regulation of glucose metabolism [34].