Furthermore, a lower risk of lymph node metastasis was related with pan-CD44 expression in oral cancer patients (RR = 0.58, 95% CI 0.37 - 0.92), but CD44-v6 expression did not reveal a similar correlation (RR = 0.79, 95% CI 0.29 - 2.12). This evidence concerns the gene CD44 and lip and oral cavity carcinoma.