Multivariate analysis confirmed that tumor diameter (P = 0.045, hazard ratio [HR]: 0.228, 95% confidence interval [CI]: 0.054-0.968) and pretreatment serum AFP level (P = 0.024, HR: 2.239, 95% CI: 1.114-4.500) were independent predictors for survival (Table 4). This evidence concerns the gene AFP and neoplasm.