According to a multivariable Cox proportional hazards model analysis, standard solution use (biocompatible solution: adjusted hazard ratio [AHR] 0.19, 95% CI 0.07-0.50; P = 0.001), but not baseline IL-6 levels (AHR 1.00, 95% CI 0.99-1.00; P = 0.74), was associated with a significantly shorter time to first peritonitis. The gene discussed is IL6; the disease is peritonitis.