NOS2A was found to be upregulated in bronchial biopsies in a microarray study (Laprise et al., 2004) and a (CCTTT)n polymorphism in the promoter region was associated with asthma phenotype studied in White population (Pascual et al., 2008) and some SNP's were found on asthmatic children having Latino and Caucasian ancestry (Islam et al., 2010). Here, NOS2 is linked to asthma.