It has been reported that Candida albicans hyphae activate NLRP3 (102, 103) and NLRP3-deficient mice succumb to both disseminated Candidiasis (102, 104) and mucosal Candidiasis (103), suggesting that the inflammasome is crucial for anti-fungal host defense. Here, NLRP3 is linked to Candidiasis, Invasive.