TYR and neoplasm: GILT has been shown to enhance MHC class II-restricted presentation of multiple epitopes from disulfide bond-containing antigens, including the model antigen hen egg lysozyme (3), tumor antigens tyrosinase and tyrosinase-related protein 1 (4, 6), viral glycoproteins (7), autoantigen myelin oligodendrocyte glycoprotein (8), and dust mite allergen Der p 1 (9).