MAPT and Alzheimer disease: Interestingly, Tau phosphorylation and/or Aβ oligomerization/aggregation have been observed in several diabetic mouse or rabbit models, confirming a possible relationship between AD disease and diabetes (Li et al., 2007; Planel et al., 2007; Jolivalt et al., 2010; Bitel et al., 2012; Papon et al., 2013).