Indeed, nuclear foci can sequester MBNL1 proteins in pathologies with CUG, CCUG, or CAG, CGG repeat expansions (Miller et al., 2000; Fardaei et al., 2002; Rudnicki et al., 2007; de Mezer et al., 2011) and hnRNPK in SCA10 (White et al., 2010) and Sam68 in FXTAS (CGG expansion), which also recruit MBNL1 and hnRNPG in foci (Iwahashi et al., 2006; Sellier et al., 2010). Here, MBNL1 is linked to fragile X-associated tremor/ataxia syndrome.