CNTF and hyperinsulinemic hypoglycemia, familial, 4: In particular, we examined the expression of CNTF and CNTFRα, and the distribution of CNTF-producing and CNTF-responsive cells in the hypothalamus of mice rendered obese by a high-fat diet (HFD) or by leptin-deficiency (ob/ob mice), and in mice fed a calorie restriction (CR) diet.