DNA from the primary tumor (sample #1) was sequenced, revealing 23 candidate variants: SCN1B, PPP1R3A, GRID2, APBA2, ZNF142, ZYG11A, RBFOX1, TCF7L1, NARF, KIAA0182, TEX13B, MUC2, LRRC3, GRHL3, MUC16, TTR, UBA1, FEN1, ELAC2, NBEAL1, DSCAML1, PCDHA4, and POLR3C (Table 1). The gene discussed is TTR; the disease is neoplasm.