HAVCR1 and acute kidney injury: In conclusion, the present meta-analysis demonstrates that measurement of urinary KIM-1, a proximal tubular injury marker, appears to be a relatively good discrimination for the diagnosis of AKI in hospital-based cohorts of patients at risk of AKI, especially in patients underwent cardiac surgery after CPB 2 h to 12 h, suggesting KIM-1 might be a specific predictor for early AKI.