GPT and tuberculosis: However, treatment with rapamycin distinctly decreased ALT (P<0.005), AST (P<0.005), ALP (P<0.01), TB (P<0.05), and BA (P<0.01) in BDL-Ra group compared with BDL rats, but had little influence on ALB, and CREA, indicating the therapeutic effect of rapamycin on liver function.