GPT and chronic hepatitis B virus infection: Another study showed that baseline HBV DNA levels < 9 logs copies/mL and ALT level ≥ 2 ×ULN are associated with better long-term outcome and lower risk of YMDD mutations compared to HBV DNA levels > 9 logs copies/mL or ALT level < 2 × ULN during lamivudine treatment for chronic hepatitis B (24).