FZD3 and schizophrenia: FZD3 gene SNPs have been also studied in the context of the methamphetamine psychosis model, which shows significant association between the FDZ3 gene and vulnerability to schizophrenia; two haplotypes comprising SNP rs2241802, rs2323019, rs352203, and rs880481 have been identified as potential risk factors [195], suggesting a role for FZD3 in both schizophrenia and drug-induced psychosis.