Emamian et al. [203] showed a reduction in AKT1 protein levels and phosphorylation of GSK3β in Ser9 in post-mortem frontal cortex and hippocampus of patients with schizophrenia; similar changes were observed also in peripheral lymphocytes of patients with schizophrenia, compared to controls. The gene discussed is GSK3B; the disease is schizophrenia.