IDH1 and central nervous system cancer: In gliomas, IDH1 mutations were reported as IDH1-R132H (664/716: 92.7%), IDH1-R132C (29/716: 4.2%), IDH1-R132S (11/716: 1.5%), IDH1-R132G (10/716: 1.4%), and IDH1-R132L (2/716: 0.2%) [13].