The sunitinib single treatment is a milder treatment compared with OXi4503 as judged by the surviving tumor mass and interestingly while vimentin and ZEB1 are upregulated throughout the remaining live tumor, E-cadherin is only downregulated near the necrotic areas resulting from the treatment (Fig. 7, control and sunitinib treated). This evidence concerns the gene ZEB1 and neoplasm.