However, at 5 weeks of age, the incidence of arrhythmias with parvin KD hearts was low, similar to the 1-week time point of wild-type control (hand-Gal4 alone) and comparable to long-lived ilk and mys heterozygotes (Fig. 3 and Fig. S1) This suggests a beneficial effect of parvin KD on old hearts by preventing an age-dependent increase in AI. Here, ILK is linked to cardiac arrhythmia.