This is in accordance with observations in models of T2D where reduced translocation of GLUT1 and GLUT4 is found in the heart [48] and, the GLUT1 and GLUT4 protein levels in the membrane are related to fasting glucose levels, the higher the fasting glucose are, the lower glut concentration in the membranes of the cardiomyocytes [49]. This evidence concerns the gene SLC2A1 and type 2 diabetes mellitus.