Our model of ovarian cancer xenograft growth and its response to carboplatin and ABT-737 therapy can be described in mathematical terms by a coupled system of ordinary and partial differential equations (further details are included in the Section S1 in File S1), which govern the temporal dynamics of the following key variables: the numbers of proliferating and arrested cancer cells; the concentrations of carboplatin and ABT-737 in circulatory and cancer tissue/intracellular compartments; and the intracellular concentrations of two members of the Bcl-family (Bcl-xL and Bax). Here, BCL2L1 is linked to ovarian carcinoma.