However, the change of CD14+CD16++ non-classical monocyte count is inconsistent; CD14+CD16++ monocyte count is increased in chronic kidney disease (CKD), abdominal aortic aneurysms (AAA), sepsis, hepatitis B, human immunodeficiency virus (HIV) infection and tuberculosis, but decreased in congestive heart failure, stroke and sepsis. This evidence concerns the gene CD14 and HIV infectious disease.