Further testing for specific disease and autoimmune entities may include classic antineutrophil cytoplasmic antibodies (cANCAs), perinuclear antineutrophil antibodies (pANCAs), proteinase 3 (PR3), myeloperoidase (MPO), angiotensin converting enzyme (ACE), rapid plasma reagin (RPR), anti-Sjogren A and B antibodies, rheumatoid factor (RF), coccidioidomycosis, and human immunodeficiency virus (HIV) testing [3]. This evidence concerns the gene PRTN3 and coccidioidomycosis.