No significant correlation was found between FXYD6 expression and T stage (χ2=1.933; P=0.164), lymph node metastasis (χ2=0.899; P=0.343) and perineural invasion (χ2=2.910; P=0.088). The gene discussed is FXYD6; the disease is metastatic malignant neoplasm in the lymph nodes.