ENOX2 and cancer: Ecto-Nicotinamide Adenine Dinucleotide Oxidase Disulfide-Thiol Exchanger 2 (ENOX2) (GenBank accession no. AF207881) [6], also known as Tumor-Associated Nicotinamide Adenine Dinucleotide Oxidase (tNOX), is ideally suited as a target for early diagnosis of cancer as well as for early preventive intervention [5,7].