Thus, a genotype/phenotype classification identified five different molecular subgroups of HCA: (i) hepatocyte nuclear factor 1 homeobox A (HNF1A) mutated, (ii) inflammatory, (iii) catenin (cadherin-associated protein) beta 1 (CTNNB1) mutated, (iv) inflammatory and CTNNB1 mutated, and (v) unclassified. This evidence concerns the gene CTNNB1 and hepatocellular adenoma.