In addition, measurements of serum Trx1 levels in the female normal control (n = 50) and the breast (n = 197) and other cancer groups (n = 111 for non-small cell lung cancer, n = 64 for CRC, and n = 30 for KC) were subjected to ROC curve analysis, and the results are summarized in Table 3. This evidence concerns the gene TXN and keratoconus.