To examine the selectivity of the blood marker Trx1 for breast cancer, the data of serum Trx1 levels for breast cancer in comparison to other cancers of shown in Figure 2 (lung cancer (LC), kidney cancer (KC) and colorectal cancer (CRC) was subjected to ROC curve analysis, and the results are shown in Table 4. Here, TXN is linked to laryngotracheoesophageal cleft.