In metastases of uveal melanomas, several proteins were found to be upregulated: Colony stimulating factor 2, Ficolin precursor, Haptoglobin -2 precursor, Hemopexin precursor, α-1-antitrypsin precursor, α-1-antichymotrypsin precursor, Vitronectin precursor, and Down syndrome cell adhesion molecule [101]. This evidence concerns the gene VTN and uveal melanoma.