(2) A significant association between p22phox gene A640G polymorphism and CAD was found under an allelic model (OR 0.84; 95% CI 0.75–0.93), dominant model (OR 0.77; 95% CI 0.64–0.92) and recessive model (OR 0.82; 95% CI 0.69–0.97). The gene discussed is CYBA; the disease is coronary artery disorder.