Accordingly, the expression of TLR4 (FC in CD16− monocytes/CD16+ monocytes; FC 1.9/1.7 in SLE, FC 1.3/1.4 in immunised ND), TLR7 (FC 1.4/2.3 in SLE, FC 1.8/1.9 in immunised ND) and DDX58/RIG-1 (FC in CD4+ T cells/CD16− monocytes/CD16+ monocytes; 2.1/2.6/2.8 in SLE, FC 2.1/3.4/2.7 in immunised ND) were upregulated in all cell types from the patients with SLE and immunised ND (Table S4). The gene discussed is TLR7; the disease is systemic lupus erythematosus.