Thus, 220 probe-sets in the CD4+ T cells from the SLE patients, 80 probe-sets in the CD4+ T cells from the immunised ND, 342 probe-sets in the CD16− monocytes from the SLE patients, 149 probe-sets in the CD16− monocytes from the immunised ND, 312 probe-sets in the CD16+ monocytes from the SLE patients and 117 probe-sets in the CD16+ monocytes from the immunised ND were identified as the top transcripts associated with type I IFN responses (Table 1 and Figure 1C). The gene discussed is CD4; the disease is systemic lupus erythematosus.