EIF2AK2 and systemic lupus erythematosus: The top ranked pathways identified in the CD16− monocytes from the SLE patients were “role of PKR (protein kinase-R; serine/threonine protein kinase) in interferon induction and antiviral response”, “IL-10 signalling” and “Fcγ receptor-mediated phagocytosis in macrophages and monocytes” (Figure 7C and Table S6).