Upon analysing the complete list of differentially expressed genes, it was obvious that SLE resulted a much more complex immune response in both the CD4+ T cells (3610 probe-sets) and the monocyte subsets (4222 probe-sets in CD16− and 3785 in CD16+ monocytes) when compared to the pure virus-induced gene pattern (Table 1 and Figure 1A). The gene discussed is CD4; the disease is systemic lupus erythematosus.