Furthermore, presence of TK suicide protein in the western blot analysis confirms the activity of the EpCAM promoter and lack of let-7b miRNAs for transcriptional regulation of suicide gene in these cell lines (Figure7C).These results are in accordance with the results obtained using Y79 and WERI-Rb1 retinoblastoma cell lines. This evidence concerns the gene RB1 and retinoblastoma.