APP and neuroblastoma: Moreover, interactions between Aβ and sequences within the APP and BACE1 promoters have been reported by the use of Chip assays on human neuroblastoma cells (Bailey et al., 2011) and by electrophoretic mobility shift assays (EMSA) indicating that Aβ peptide may regulate genes involved in its own production (Maloney and Lahiri, 2011).