CSF3 and acute myeloid leukemia: In a study performed by Wei et al., the HAG regimen (G-CSF 200 μg m-2, beginning from one day prior to chemotherapy until WBC > 20 × 109 L-1 for 14 ~ 28 d, Ara-C 10 mg m-2, 1/12 h, for 14 ~ 28 d, HHT l ~ 2 mg m-2 for 14 ~ 28 d) was used to treat 20 refractory AML patients, which resulted in a CR rate of 70% [76].