The typical multilaminar arrangement of the tumour VBM, that is a hallmark of the "garland vessels" phenotype [10,35,36,43], was revealed on sections immunolabelled with anti-Coll IV and with NG2/CSPG4 D2 antiserum, which also recognized fragmented PG, possibly released by cell surface proteolysis (Figure 1D, E, H, I; Figure S4A, C, D, F). The gene discussed is CSPG4; the disease is neoplasm.