NID1 and hydrops fetalis: In addition, dispase-pretreated organ-cultured adult human scalp HF epithelium, which lacks normal HF BM and mesenchyme, was embedded into Matrigel®, since the latter is rich in ECM components that are also found in the HF’s CTS and BM, such as laminin, collagen IV, heparin sulfate proteoglycans, entactin, and growth factors [12,35], with collagen I added for structural support and for mimicking any signaling input of dermal collagen.