We chose four genes BTF3, NDRG1, HINT1 and ODC1 that are up-regulated in prostate carcinoma (oncomine.org; selection criteria: p=0.0001, 2 fold change and in top 10% of genes over-expressed in the overall dataset) in at least four normal vs cancer prostate gene expression analysis datasets [11–14]. This evidence concerns the gene HINT1 and cancer.