RNASE1 and neoplasm: qPCR analysis confirmed the discovered tendency for an increase in the levels of miRNAs in the tumour and decrease in the levels of miRNAs in the serum after treatment with RNase A. An approximate two-fold increase in miRNA level in the tumour tissue (Figure 4A) and an approximate two-fold reduction in miRNA level in the blood serum were observed (Figure 4B).