Expression of Nectin-1 and Nectin-2 was higher in ductal carcinomas than in all other histological types (Nectin-1: ductal 348+/−122 versus other 112+/−27, p = 0.063; Nectin-2: ductal 104+/−93 versus other 82+/−38, p = 0.0037). Here, NECTIN1 is linked to breast ductal adenocarcinoma.