However, we did identify ∼60% of HCC with elevated expression of ADAR1, which is consistent with the results reported by Chan et al. However, none of the cases with ADAR1 elevation only showed the editing events at miR-214 and miR-122 related transcripts identified in the current study, suggesting these editing events are not attributed by overexpressed ADAR1. The gene discussed is ADAR; the disease is hepatocellular carcinoma.