FOXC1 and cleft palate-lateral synechia syndrome: The recent generation of a conditional Foxc1 allele [30] and increased understanding of the role of Foxc1 within neural crest-derived populations, as well as the relationship between abnormally patterned skeletal elements and their associated muscles, will enhance our collective knowledge of jaw development and inform treatment strategies for human patients with syngnathia and other related craniofacial malformations.