Although Ichikawa et al. reported that patients who had high p53 expression had increased LDH levels and advanced-stage disease [21], Sanchez et al. [5], Kramer et al. [6], Wilson et al. [19], and Rujirojindakul et al. [23] did not demonstrate statistical correlation between p53 expression and age, sex, LDH level, and B symptoms in patients with DLBCL. Here, TP53 is linked to diffuse large B-cell lymphoma.