Mean decreasein IgG ranged from 27% to 32% in other studies [25,27].Although acute mean reductions of 59.7% in fibrinogen,21.5% in serum protein, 14.7% in serum albumin, and14.2% in platelets were noted, we did not observe any infection,hemorrhagia, or edema in our patients. The gene discussed is ALB; the disease is infection.