VWF and von Willebrand disease 3: Clinicaldiagnosis of type 3 vWD is easily made based on phenotypictesting, as vWF is completely absent in the plasma.Nevertheless, genetic testing of type 3 vWD patients couldbe used for genetic counseling, prenatal diagnosis, andpredicting inhibitor formation; however, the whole genemust be analyzed because mutations are scattered alongthe vWF gene.