Moreover, TAA-induced HE was associated with increased conversion of Arg to neurotransmitters Glu and γ-aminobutyric acid (GABA), a process engaging increased activities of arginase (AR; EC 3.5.3.1) and ornithine aminotransferase (OAT; EC 2.6.1.13) (Albrecht et al. 1990). The gene discussed is OAT; the disease is hereditary elliptocytosis.