Importantly, using a xenograft mouse model with intraperitoneally injected ovarian carcinoma cells we showed that ovarian carcinoma dissemination to the peritoneal wall and diaphragm strongly depended on XCR1 expressed by the ovarian cancer cells, suggesting the presence of lymphotactin-dependent mechanisms supporting metastatic cell homing to these sites [57]. The gene discussed is XCL1; the disease is ovarian cancer.