Univariate and multivariate analysis reveal that 5-year survival rate is 72.41% in the 26 cases with lower IL-17 expression and 38.08% in the 26 cases with higher IL-17 expression, proposing that IL-17 is an independent prognostic factor for overall survival and IL-17 producing cells may facilitate development of CRC by fostering angiogenesis via stimulation of VEGF production by cancer cells [52]. Here, VEGFA is linked to colorectal carcinoma.