By Spearman analysis, MPV correlated with the PLC (r: –0.38, P < 0.001), age (r: −0.21, P = 0.04), presence of hypercholesterolemia (r: −0.22, P = 0.038), and presence of antidepressant use (r: 0.25, P = 0.017) in AD patients. This evidence concerns the gene HSPG2 and Hypercholesterolemia.